Preheat oven to 350°F. Place pepitas, almonds, brown sugar, ginger and salt in food processor; cover. Pulse until coarsely chopped. Add butter; mix until well blended. Press firmly onto bottom and up sides of pie plate.
Bake 8 to 10 minutes or until lightly browned.
Mix pumpkin, milk, eggs and vanilla in large bowl until smooth. Add spices; mix until well blended. Pour into prepared crust on large foil-lined baking sheet.
Bake 40 to 45 minutes or until knife inserted 1 inch from crust comes out clean. Cool on wire rack.