Preheat oven to 350 degrees F. Lightly grease a 9-inch loaf pan.
In medium bowl, blend together pumpkin bread mix, water, oil, and 2 eggs. Set aside.
Place cream cheese in separate bowl. Whisk cream cheese until smooth. Add 1 egg, sugar, and vanilla. Whisk again to combine. Spoon half of mixture into another small bowl, and add 2 teaspoons of cinnamon. Stir until smooth.
Spoon half of the bread batter into prepared pan. Spoon half of the plain cream cheese mixture and half of the cinnamon cream cheese mixture on top, swirl with a knife. Add remaining bread batter, and layer with remaining cream cheese mixtures.
Bake 52–55 minutes, or until toothpick inserted into center comes out clean.